The Medication Interaction, Examined
L-Citrulline, one of Baking Soda Trick's named ingredients, works on a pathway shared with certain prescription medications.
Understanding this interaction is important if you take blood pressure, nitrate, or ED medication.
What the interaction is
L-Citrulline converts to L-Arginine in the body, which supports nitric oxide production — the same pathway targeted by prescription ED medications (like sildenafil or tadalafil) and by nitrate medications used for chest pain (angina).
Who should be especially careful
Anyone taking prescription nitrates, blood pressure medication, blood thinners, or ED medication should talk to their doctor before starting Baking Soda Trick or any similar L-Citrulline-containing supplement.
What we'd encourage
Bring the full ingredient list to your doctor or pharmacist if you take any of the medications above, and let them make the call on whether this supplement is appropriate alongside your specific prescriptions.
Applying this to Baking Soda Trick
See our full ingredient transparency page for the complete picture, and our 90-day assessment for our overall take.
